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Dual-targeted STAb-T cells secreting BCMA and CD19 T cell engagers for improved control of haematological cancers

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Despite recent advances in immunotherapy against B cell malignancies such as BCMA (B cell maturation antigen) and CD19-targeted treatments using soluble T cell-engaging (TCE) antibodies or chimeric antigen receptor T cells (CAR-T), there is still an important ... ...