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Kinetic Analysis of Cyclization by the Substrate-Tolerant Lanthipeptide Synthetase ProcM

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Lanthipeptides are ribosomally synthesized and post-translationally modified peptides (RiPPs) characterized by the presence of thioether cross-links called lanthionine and methyllanthionine, formed by dehydration of Ser/Thr residues and Michael-type addition o... ...