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WD repeat domain 5 (WDR5) inhibitors: a patent review (2016-present)

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Introduction: WDR5 is an epigenetic scaffolding protein that has attracted significant interest as an anti-cancer drug target, especially in MLL-rearranged leukemias. The most druggable 'WIN-site' on WDR5, which tethers WDR5 to c... ...