Isoform-specific N-linked glycosylation of NaV channel α-subunits alters β-subunit binding sites
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Voltage-gated sodium channel α-subunits (NaV1.1-1.9) initiate and propagate action potentials in neurons and myocytes. The NaV β-subunits (β1-4) have been shown to modulate α-subunit properties. Homo-oligomerization of β-subunits on neighboring or opposin... ...
