Background: Situs inversus is a congenital malformation that occurs in one or multiple organs simultaneously and can be accompanied by malformations in other body parts. We analyzed the prevalence and phenotype of patients with situs inversus and comorbidities associated with other plastic surgery-related malformations to enhance the knowledge of its related disorders and facilitate treatment.

Methods: We recruited patients with situs inversus who were seen at our institution from February 2015 to July 2023. They underwent ultrasound and physical examinations to investigate deformity in other body parts. Fisher's exact test was used to analyze the laterality between hemifacial microsomia and situs inversus type.

Results: All 14 patients with situs inversus had plastic surgery-related malformations-three congenital and three developmental. Nine (65%) patients had hemifacial microsomia (right side, n = 8; bilateral, n = 1). The laterality of hemifacial microsomia was associated with the situs inversus type, with a significant difference (P < 0.05), and hemifacial microsomia occurred ipsilaterally in patients with right-sided hearts.

Conclusions: Early situs inversus diagnosis is clinically important for patients and plastic surgeons. Further studies on anomalies associated with situs inversus will improve our understanding of their etiology.

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背景： 镜像反转（Situs inversus）是一种先天性畸形，可能同时影响一个或多个器官，并且常常伴有其他身体部位的畸形。我们分析了患有镜像反转及其与整形手术相关畸形有关联的并发症患者的发病率和表型，以增强对其相关疾病的了解并促进治疗。

方法： 我们招募了2015年2月至2023年7月期间在我机构就诊的所有患有镜像反转的患者。他们接受了超声波检查和身体检查，以调查其他身体部位是否出现畸形。使用Fisher确切概率检验来分析半侧颜面短小症与镜像反转类型的不对称性。

结果： 所有14名患有镜像反转的患者均存在整形手术相关的畸形，其中有3例先天性和3例发育性的。9（65%）名患者有半侧颜面短小症（右侧8例；双侧1例）。半侧颜面短小症与镜像反转类型的不对称性显著相关（P

结论： 早期诊断镜像反转对患者和整形外科医生临床上非常重要。进一步研究与镜像反转相关的异常将有助于我们更好地了解其病因。