APC orchestrates microtubule dynamics by acting as a positive regulator of KIF2A and a negative regulator of CLASPs
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Tumor suppressor protein Adenomatous polyposis coli protein (APC) is an EB-binding and microtubule (MT) plus end-tracking protein; however, how exactly APC regulates MT dynamics remains elusive. Here, we show that in LLC-PK1 cells, APC and KIF2A, an MT depolym... ...