Insights into biofilm architecture and maturation enable improved clinical strategies for exopolysaccharide-targeting therapeutics
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Polysaccharide intercellular adhesin (PIA), an exopolysaccharide composed of poly-N-acetyl glucosamine (PNAG), is an essential component in many pathogenic biofilms. Partial deacetylation of PNAG is required for biofilm formation, but limited structural knowle... ...
