β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain
{{output}}
Loss of proteostasis is a hallmark of aging and Alzheimer disease (AD). We identify β-hydroxybutyrate (βHB), a ketone body, as a regulator of protein solubility. βHB primarily provides ATP substrate during periods of reduced glucose availability, and regula... ...
