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Cortical Functional Connectivity Changes in the Body-First and Brain-First Subtypes of Parkinson's Disease

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Background: Rapid eye movement (REM) sleep behavior disorder (RBD) may precede motor symptoms in Parkinson's disease (PD) by years. According to a recent hypothesis, premotor RBD (pRBD) is a marker of the PD body-first subtype, w... ...