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Sexual dimorphism in prokinetic effects of a ghrelin agonist acting through the lumbosacral defecation center in rats

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We investigated the effects of a centrally penetrant ghrelin agonist, RQ-00538053, on colorectal motility in female rats in comparison with that in male rats. Intravenous administration of RQ-00538053 enhanced colorectal motility in female rats. However, appro... ...