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Stereospecific Properties and Intracellular Transport of Novel Intrinsically Fluorescent Neurosteroids

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Allopregnanolone (AlloP) is an example of neuroactive steroids (NAS), which is a potent allosteric activator of the γ-aminobutyric acid A (GABAA) receptor. The mechanisms underlying the biological activity of AlloP and other NAS are only partially understood.... ...