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EMCV VP2 degrades IFI16 through Caspase-dependent apoptosis to evade IFI16-STING pathway

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Interferon (IFN)-γ inducible protein 16 (IFI16), a key DNA sensor, triggers downstream STING-dependent type I interferon (IFN-I) production and antiviral immunity. However, how the IFI16-STING signaling pathway is regulated by EMCV infection is still not well... ...