Tubulin acetyltransferases access and modify the microtubule luminal K40 residue through anchors in taxane-binding pockets
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Acetylation at α-tubulin K40 is the sole post-translational modification preferred to occur inside the lumen of hollow cylindrical microtubules. However, how tubulin acetyltransferases access the luminal K40 in micrometer-long microtubules remains unknown. He... ...