Background: The incidence of lung cancer is unequally distributed in France. Although several studies have shown a link between the socioeconomic environment of populations and the incidence of cancer, the contribution has not been quantified. We aimed to analyse the geographical variability of lung cancer incidence in Normandy and calculate the proportion explained by the socioeconomic environment.

Methods: We included 7665 lung cancer cases recorded in the General Tumor Registry of Calvados and the Cancer Registry of Manche. A Bayesian model was used to map the spatial variation in the incidence of lung cancer in the territory, and an innovative approach was used to evaluate the influence of geographical variability in the socioeconomic environment on the spatial heterogeneity of lung cancer incidence.

Results: The maps of the spatial components showed high contrasts for both genders, and the socioeconomic environment integration in the model made the maps less contrasting. The socioeconomic environment of the population explained one-third of the spatial variation in the incidence of lung cancer in women and one-fifth in men.

Conclusion: The results showed that a non-negligible part of the spatial variation in the incidence of lung cancer could be explained by the geographical distribution of the socioeconomic environment.

Keywords: EPIDEMIOLOGY; Health inequalities; LUNG CANCER; SPATIAL ANALYSIS.

© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

背景： 法国肺癌的发病率分布不均。尽管已有研究表明人口的社会经济环境与癌症发病率之间存在关联，但这种贡献尚未量化。我们的目标是分析诺曼底地区的肺癌发病率地理差异，并计算社会经济环境对其影响的比例。

方法： 我们纳入了在卡勒瓦斯综合肿瘤登记处和芒什癌症登记处记录的7665例肺癌病例。使用贝叶斯模型来绘制该地区肺癌发病率的空间变化，并采用创新的方法评估地理上社会经济环境差异对肺癌发病率空间异质性的影响。

结果： 空间组件的地图显示了性别间的高度对比，而将社会经济因素纳入模型后，地图上的对比度有所降低。人口的社会经济状况解释了女性中三分之一的肺癌发病率地理变化和男性中五分之一的变化。

结论： 结果显示，肺癌发病率的空间变化可以部分通过社会经济环境的地理位置分布来解释。

关键词： 流行病学；健康不平等；肺癌；空间分析。