Metabolic Engineering of Glycofusion Bispecific Antibodies for α-Dystroglycanopathies
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Background: α-dystroglycanopathies are congenital muscular dystrophies in which genetic mutations cause the decrease or absence of a unique and complex O-linked glycan called matriglycan. This hypoglycosylation of O-linked matriglycan on the α-dystroglycan (... ...
