The role of interleukin-6 classic and trans-signaling and interleukin-11 classic signaling in gastric cancer cells
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Introduction: The cytokine interleukin-11 (IL-11) binds on its target cells to a membrane-bound IL-11R, which results in homodimerization of the signal-transducing β-receptor gp130. Recent studies have uncovered a pro- inflammat... ...