Design of in-situ implant for the brain-targeted drug delivery using cross-linked gellan gum polymer through response surface methodology
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The analysis aimed to prepare an in-situ implant (ISFI) formulation holding dimethyl fumarate as (a model drug) using cross-linked gellan gum by homogenization method. Cross-linking of gellan gum was done with L-cysteine to improve its gelation properties. Fou... ...