Thiourea-based rotaxanes: anion transport across synthetic lipid bilayers and antibacterial activity against Staphylococcus aureus
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We report the synthesis of two rotaxanes (1 and 2) whose rings have appended thiourea units for the selective recognition of Cl- anions. Rotaxane 1 transports Cl- across synthetic lipid bilayers more efficiently than 2, exhibiting EC50 values of 0.243 mol% ver... ...