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Molecular basis of global promoter sensing and nucleosome capture by the SWR1 chromatin remodeler

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The SWR1 chromatin remodeling complex is recruited to +1 nucleosomes downstream of transcription start sites of eukaryotic promoters, where it exchanges histone H2A for the specialized variant H2A.Z. Here, we use cryoelectron microscopy (cryo-EM) to resolve th... ...