Inhibition of hERG K channels by verapamil at physiological temperature: Implications for the CiPA initiative
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The Comprehensive in vitro Proarrhythmia Assay (CiPA) initiative reassesses using the inhibition of hERG potassium channels by drugs as the major determinant for the potential to cause drug-induced Torsades de Pointes (TdP) cardiac arrhythmias. Here we report ... ...