ATXN3: a multifunctional protein involved in the polyglutamine disease spinocerebellar ataxia type 3
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ATXN3 is a ubiquitin hydrolase (or deubiquitinase, DUB), product of the ATXN3 gene, ubiquitously expressed in various cell types including peripheral and neuronal tissues and involved in several cellular pathways. Importantly, the expansion of the CAG trinucle... ...
