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A Multimodal, In Vivo Approach for Assessing Structurally and Phenotypically Related Neuroactive Molecules

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A recently reported behavioral screen in larval zebrafish for phenocopiers of known anesthetics and associated drugs yielded an isoflavone. Related isoflavones have also been reported as GABAA potentiators. From this, we synthesized a small library of isoflavo... ...