Requirement of the N-terminal region of nonstructural protein 1 in cis for SARS-CoV-2 defective RNA replication
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SARS-CoV-2 belongs to the family Coronaviridae and carries a single-stranded positive-sense RNA genome. During coronavirus (CoV) replication, defective or defective interfering RNAs that lack a large portion of the genome often emerge. These defective RNAs typ... ...