A phase I safety and efficacy clinical trial of plocabulin and gemcitabine in patients with advanced solid tumors
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Plocabulin (Plo) induces depolymerization of tubulin fibers with disorganization and fragmentation of the microtubule network leading to mitosis. Plo combined with gemcitabine (Gem) showed synergistic anti-tumor activity in preclinical studies. This phase I tr... ...
