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Adenosine deaminase 2 regulates the activation of the toll-like receptor 9 in response to nucleic acids

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Human cells contain two types of adenosine deaminases (ADA) each with unique properties: ADA1, which is present in all cells where it modulates intracellular functions and extracellular signaling, and ADA2, which is secreted by immune cells. The exact intracel... ...