The downregulation of SCGN induced by lipotoxicity promotes NLRP3-mediated β-cell pyroptosis
{{output}}
Lipotoxicity is a well-established phenomenon that could exacerbate damage to islet β-cells and play a significant role in the development of type 2 diabetes, the underlying mechanisms of which, however, remain unclear. In lipotoxic conditions, secretagogin (... ...