Roles of astrocytic sonic hedgehog production and its signal for regulation of the blood-brain barrier permeability
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Sonic hedgehog (Shh) is a secreted glycopeptide belonging to the hedgehog family that is essential for morphogenesis during embryonic development. The Shh signal is mediated by two membrane proteins, Patched-1 (Ptch-1) and Smoothened (Smo), following the activ... ...
