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TREK-1 channel as a therapeutic target for dexmedetomidine-mediated neuroprotection in cerebral ischemia

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Our objective is to explore the protective effect of Dexmedetomidine on brain apoptosis and its mechanism through TREK-1 pathway. Forty male Sprague-Dawley rats were allocated into four groups: Sham, Cerebral Ischemia/Reperfusion Injury (CIRI), 50 µg/kg Dex, ... ...