TaqTth-hpRNA: a novel compact RNA-targeting tool for specific silencing of pathogenic mRNA
{{output}}
Pathogenic allele silencing is a promising treatment for genetic hereditary diseases. Here, we develop an RNA-cleaving tool, TaqTth-hpRNA, consisting of a small, chimeric TaqTth, and a hairpin RNA guiding probe. With a minimal flanking sequence-motif requireme... ...
