首页 正文

Clinical transplantation. 2024 Jul;38(7):e15381. doi: 10.1111/ctr.15381 Q21.92025

A Tailored Virtual Program for Alcohol Use Disorder Treatment Among Liver Transplant Candidates and Recipients Is Feasible and Associated With Lower Post-Transplant Relapse

针对肝移植受者和候选者的定制虚拟酒精使用障碍治疗项目是可行的,并且与移植后的较低复发率相关 翻译改进

Arpita Goswami  1, Ethan Weinberg  2, Lynda Coraluzzi  3, Therese Bittermann  2  4, Jonathan Nahas  2, Senayish Addis  5, Robert Weinrieb  1, Marina Serper  2  6

作者单位 +展开

作者单位

  • 1 Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • 2 Division of Gastroenterology and Hepatology, School of Medicine, University of Pennsylvania Perelman, Philadelphia, Pennsylvania, USA.
  • 3 Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, USA.
  • 4 Center for Clinical Epidemiology and Biostatistics, School of Medicine, University of Pennsylvania Perelman, Philadelphia, Pennsylvania, USA.
  • 5 Penn Transplant Institute, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • 6 Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • DOI: 10.1111/ctr.15381 PMID: 38940230

    摘要 Ai翻译

    Background: Alcohol-associated liver disease (ALD) is a leading indication for liver transplant (LT) in the United States. Rates of early liver transplant (ELT) with less than 6 months of sobriety have increased substantially. Patients who receive ELT commonly have alcohol-associated hepatitis (AH) and are often too ill to complete an intensive outpatient program (IOP) for alcohol use disorder (AUD) prior to LT. ELT recipients feel alienated from traditional IOPs.

    Methods: We implemented Total Recovery-LT, a tailored virtual outpatient IOP specific for patients under evaluation or waitlisted for LT who were too ill to attend community-based alcohol treatment programs. The 12-week program consisted of weekly group and individual counseling delivered by a master's level Certified Addiction Counselor trained in the basics of LT. Treatment consisted of 12-Step Facilitation, Motivational Interviewing, and Cognitive Behavioral Therapy. We report on program design, implementation, feasibility and early outcomes.

    Results: From March 2021 to September 2022, 42 patients (36% female, 23 in LT evaluation, 19 post-transplant) enrolled across five cohorts with 76% (32/42) completing the program. Alcohol relapse was more common among noncompleters versus those who completed the program (8/10, 80% vs. 7/32, 22%, p = 0.002). History of trauma or post-traumatic stress symptoms were associated with lower likelihood of completion. Patients' desire for continued engagement after completion led to the creation of a monthly alumni group.

    Conclusions: Our integrated IOP model for patients with high-risk AUD in LT evaluation or post-transplant is well-received by patients and could be considered a model for LT programs.

    Keywords: alcohol‐associated hepatitis; integrated care; intensive outpatient program; telehealth.

    Keywords:alcohol use disorder treatment; liver transplant candidates; virtual program; post-transplant relapse

    Copyright © Clinical transplantation. 中文内容为AI机器翻译,仅供参考!

    相关内容

    期刊名:Clinical transplantation

    缩写:CLIN TRANSPLANT

    ISSN:0902-0063

    e-ISSN:1399-0012

    IF/分区:1.9/Q2

    文章目录 更多期刊信息

    全文链接
    引文链接
    复制
    已复制!
    推荐内容
    A Tailored Virtual Program for Alcohol Use Disorder Treatment Among Liver Transplant Candidates and Recipients Is Feasible and Associated With Lower Post-Transplant Relapse