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Down-regulation of ABCB1 in Everolimus-resistant Renal Cell Carcinoma Cells

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Background/aim: Everolimus-resistant Caki/EV and 786/EV cells have been established from human derived renal cell carcinoma cells, Caki-2 and 786-O, respectively. These cells exhibit resistance to everolimus and to other mTOR inh... ...