Expression and purification of active human 17β-Hydroxysteroid dehydrogenase type 1 from Escherichia coli
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Breast cancer cell growth is often dependent on the presence of steroidal hormones. The 17β-hydroxysteroid dehydrogenase type 1 isoform (17βHSD1) catalyzes NADPH-dependent conversion of estrone to estradiol, a more potent estrogen, and represents potential d... ...
