Predictive role of ITPA genetic variants in thiopurine-related myelotoxicity in Crohn's disease patients
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Thiopurines, an effective therapy for Crohn's disease (CD), often lead to adverse events (AEs). Gene polymorphisms affecting thiopurine metabolism may predict AEs. This retrospective study in CD patients (n = 114) with TPMT activity > 5 Units/Red Blood Cells a... ...
