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Muscle fibrosis, NF-κB, and TGF-β are differentially altered in two models of paralysis (Botox vs. Neurectomy)

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Objective: Volumetric muscle loss (VML) results in intramuscular axotomy, denervating muscle and leading to paralysis and loss of muscle function. Once the nerve is damaged, paralyzed skeletal muscle will atrophy and accumulate n... ...