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A high-throughput focused collimator for OAR-sparing preclinical proton FLASH studies: commissioning and validation

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Objective. To fabricate and validate a novel focused collimator designed to spare normal tissue in a murine hemithoracic irradiation model using 250 MeV protons delivered at ultra-high dose rates (UHDRs) for preclinical FLASH radiation therapy (FLASH-RT) studi... ...