Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons
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Induced pluripotent stem cell (iPSC)-derived motor neurons (MNs) from patients with amyotrophic lateral sclerosis (ALS) and the C9ORF72 hexanucleotide repeat expansion (HRE) have multiple cellular phenotypes, but which of these accurately reflect the biology u... ...
