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The F-box E3 ligase protein FBXO11 regulates EBNA3C-associated degradation of BCL6

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Most mature B-cell malignancies originate from the malignant transformation of germinal center (GC) B cells. The GC reaction appears to have a role in malignant transformation, in which a major player of the GC reaction is BCL6, a key regulator of this process... ...