Role of the membrane-associated accessory protein (MAAP) in adeno-associated virus (AAV) infection
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Adeno-associated viruses (AAVs) package a single-stranded (ss) DNA genome of 4.7 kb in their capsid of ~20 nm in diameter. AAV replication requires co-infection of a helper virus, such as adenovirus. During the optimization of recombinant AAV production, a sma... ...