The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis
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The Nod-like receptor protein 3 (NLRP3) inflammasome is activated by stimuli that induce perturbations in cell homeostasis, which commonly converge on cellular potassium efflux. NLRP3 has thus emerged as a sensor for ionic flux. Here, we identify forchlorfenur... ...
