ANGPTL3 accelerates atherosclerotic progression via direct regulation of M1 macrophage activation in plaque
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Introduction: The N-terminal domain of angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprotein lipase activity. Its C-terminal fibrinogen-like (FBN) domain is a ligand of macrophage integrin αvβ3. ... ...
