A small molecule compound 759 inhibits the wnt/beta-catenin signaling pathway via increasing the Axin protein stability
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Wnt/β-catenin signaling plays important role in cancers. Compound 759 is one of the compounds previously screened to identify inhibitors of the Wnt/β-catenin pathway in A549 cells [Lee et al. in Bioorg Med Chem Lett 20:5900-5904, 2010]. However, the mechanis... ...
