Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imaging
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Non-hematopoietic cells are essential contributors to hematopoiesis. However, heterogeneity and spatial organization of these cells in human bone marrow remain largely uncharacterized. We used single-cell RNA sequencing (scRNA-seq) to profile 29,325 non-hemato... ...