The Genetic Pathophysiology and Clinical Management of the TADopathy, X-Linked Acrogigantism
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Pituitary gigantism is a rare manifestation of chronic growth hormone (GH) excess that begins before closure of the growth plates. Nearly half of pituitary gigantism patients have an identifiable genetic cause. X-linked acrogigantism (X-LAG; 10% of pituitary g... ...