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Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity

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Human peptidylarginine deiminase isoform VI (PAD6), which is predominantly limited to cytoplasmic lattices in the mammalian oocytes in ovarian tissue, is essential for female fertility. It belongs to the peptidylarginine deiminase (PAD) enzyme family that cata... ...