首页 正文

NSC689857, an inhibitor of Skp2, produces antidepressant-like effects in mice

{{output}}
We have previously reported that two inhibitors of an E3 ligase S-phase kinase-associated protein 2 (Skp2), SMIP004 and C1, have an antidepressant-like effect in non-stressed and chronically stressed mice. This prompted us to ask whether other Skp2 inhibitors ... ...