Cortactin-dependent control of Par1b-regulated epithelial cell polarity in Helicobacter infection
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Cell polarity is crucial for gastric mucosal barrier integrity and mainly regulated by polarity-regulating kinase partitioning-defective 1b (Par1b). During infection, the carcinogen Helicobacter pylori hijacks Par1b via the bacterial oncoprotein CagA leading t... ...