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The malignant transformation potential of the oncogene STYK1/NOK at early lymphocyte development in transgenic mice

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B-cell Chronic Lymphocytic Leukemia (B-CLL) is a malignancy caused by the clonal expansion of mature B lymphocytes bearing a CD5+CD19+ (B1) phenotype. However, the origin of B-CLL remains controversial. We showed previously that STYK1/NOK transgenic mice devel... ...