The proprotein convertase FURIN is a novel aneurysm predisposition gene impairing TGF-β signaling
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Aim: Aortic aneurysms (AA) frequently involve dysregulation of transforming growth factor β (TGF-β)-signaling in the aorta. Here, FURIN was tested as aneurysm predisposition gene given its role as proprotein convertase in pro-T... ...
