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Tanshinone IIA destabilizes SLC7A11 by regulating PIAS4-mediated SUMOylation of SLC7A11 through KDM1A, and promotes ferroptosis in breast cancer

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Introduction: Breast cancer (BC) is the most common malignancy in women with unfavorite prognosis. Objectives: Tanshinone IIA (Tan IIA) inhibit... ...