Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation
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Aims: The interleukin-1 receptor accessory protein (IL1RAP) is a co-receptor required for signalling through the IL-1, IL-33, and IL-36 receptors. Using a novel anti-IL1RAP-blocking antibody, we investigated the role of IL1RAP in... ...
